Greenbrook Mental Wellness Centers
223 Adley Way, Greenville
4.6(19 Google reviews)
Treatment information
Ketamine treatment
Ketamine is not FDA-approved specifically for OCD. Research is preliminary, and a response to ketamine in depression does not establish that it treats OCD. Ask a clinician about exposure and response prevention, medication and the evidence and risks for any off-label option.
Tell us a little about you. A care coordinator will match you with a ketamine clinic near you.

Greenville County · South Carolina
No clinic is currently listed inside Simpsonville. The closest listed option is 5.9 straight-line miles away, in Greenville.
Independent directory · confirm services and addresses directly. Educational information, not medical advice.
Request a Free Consultation →Serving Simpsonville and nearby communities — we'll help you find the closest available provider.
For Simpsonville residents in Greenville County, the directory options are in Greenville, not confirmed Simpsonville offices. They are regional comparisons rather than a complete inventory of available care. Start with the treatment being considered, then ask whether the selected office can support your assessment, monitoring and continuing care.
Greenbrook Mental Wellness Centers lists Spravato nasal spray. Infused Greenville, Greenville Ketamine Center lists ketamine infusion therapy. Life Line Services - Healing Substance Abuse publishes ketamine-assisted treatment at its Mills Avenue office, but the description does not specify an administration route. Ask that practice directly rather than assuming it provides infusions, injections or nasal treatment.
A licensed physician should assess your diagnosis, medical history, current medicines and prior treatment history before a treatment decision. Bring information about previous medication trials and psychotherapy, including benefits and difficulties. Ask how the proposed plan will be coordinated with your existing prescriber or therapist and how follow-up decisions will be made. Evidence differs by diagnosis; information about depression should not be treated as evidence for every other condition.
Ketamine is approved for anesthesia; psychiatric IV, IM and compounded ketamine use is off-label. Spravato is esketamine with specific FDA-approved adult depression indications, not blanket approval for all psychiatric uses of ketamine.
For additional community context, compare Mauldin, Greenville and Greer. Confirm current services at the selected address and whether appointments are available.
Directory sources and official guidance reviewed November 3, 2026. Confirm current clinic services directly; educational information, not medical advice.
Treatment schedules vary by clinic and treatment type, so plan transportation for each visit. Distances below are straight-line miles from Simpsonville.
5.9 miles away · Greenville
223 Adley Way, Greenville
4.6(19 Google reviews)
Treatment information
8.6 miles away · Greenville
35 Creekview Court, Greenville
4.7(44 Google reviews)
Treatment information
10.8 miles away · Greenville
16 Mills Avenue, 8, Greenville
4.3(10 Google reviews)
Treatment information
10.8 miles away · Greenville
16 Mills Avenue, Unit 6, Greenville
4.8(200 Google reviews)
Treatment information
24.8 miles away · Spartanburg
230 North Grove Medical Park Drive, Spartanburg
4.9(20 Google reviews)
Treatment information
Before committing to travel from Simpsonville, request a written, itemized estimate from the selected office. It should separate assessment, medication, administration and monitoring, psychotherapy if provided, follow-up and possible maintenance treatment. Add transportation and any escort-related expenses to your own budget. Ask what is charged if the physician determines you are not eligible, and whether future visits are priced separately from an initial course.
IV and compounded ketamine are often self-pay. A listing for ketamine-assisted treatment does not establish what services are bundled or which route is billed.
For Spravato, benefits, prior authorization, network participation and cost sharing vary. Ask both the clinic and insurer about the selected address and each billed component. Do not assume Medicare or Medicaid coverage or that authorization removes all out-of-pocket costs.
The FDA warning about compounded ketamine includes psychiatric home use. A lower advertised home-treatment price is not evidence of equivalent oversight, and a telehealth evaluation does not replace required monitoring.
Ask the office for an individualized assessment and visit schedule before arranging travel. Confirm the treatment address, assessment arrangements, monitoring and discharge rules before arranging time away from work or other responsibilities. For routes other than Spravato, follow the clinician’s instructions and arrange responsible adult pickup.
Spravato requires a certified, supervised setting and monitoring for at least two hours. The FDA prescribing information says not to drive until the next day after restful sleep. Build that restriction into both the trip home and later obligations. Transit or rideshare alone is not automatically an acceptable escort; ask the office what it requires.
Use the SCDOT transit-provider directory only as a starting point, then confirm routes, schedules and eligibility directly. No transportation arrangement is established by this guide.
Ask your existing clinician how records and follow-up will be shared. The BHDD mental health center directory identifies county-based community resources, not proof of ketamine services. This directory does not provide emergency intake. For crisis support, call or text 988; for an emergency, call 911.
The options are Greenville offices, not established Simpsonville locations. Greenbrook, Infused Greenville and Life Line Services are regional comparisons, not an exhaustive list. Confirm the exact treatment address and current services before planning a visit; inclusion in the directory does not mean a practice is accepting new patients.
Greenbrook lists Spravato nasal spray, while Infused Greenville lists ketamine infusion therapy. Life Line Services publishes ketamine-assisted treatment at its Mills Avenue office without a specified route in the description. Ask about the actual treatment, physician assessment and monitoring rather than treating these descriptions as interchangeable.
Bring your current medication list, relevant medical history and details of previous psychiatric treatments, including duration, response and side effects. Ask your existing clinician about sharing records with the assessing physician. The appointment should address your diagnosis and goals, not simply select a route based on convenience or price.
No. Spravato requires supervised administration, at least two hours of monitoring and no driving until the next day after restful sleep. Arrange transportation before the visit and ask whether a responsible adult must accompany you. A rideshare booking does not by itself establish that the office’s discharge requirements are met.
Only after checking what each figure includes. Request itemized assessment, medication, monitoring, psychotherapy if offered and maintenance costs, then add travel from Simpsonville. Spravato benefits and authorization vary, while IV ketamine is often self-pay. Neither a quoted copay nor a package headline necessarily represents your complete financial commitment.
Ask the treatment office to coordinate with your existing prescriber or therapist, with your permission. Agree on who manages routine medication questions, follow-up and concerns between visits. County community mental health resources may help with ongoing care, but their presence does not establish that they offer ketamine treatment.
Costs, coverage & aftercare
IV, IM and compounded ketamine for psychiatric conditions are off-label; many programs are self-pay. Ask about assessment, medication, administration, monitoring, therapy and maintenance charges separately. We do not assume a statewide price.
Spravato is FDA-approved esketamine, not the same as ketamine infusions. Coverage is not guaranteed. Check eligibility, prior authorization, network status, drug and visit charges, deductibles and copays with your insurer and clinic.
Spravato requires a certified healthcare setting and monitoring for at least two hours. Arrange transport home; do not drive until the next day after restful sleep. For other ketamine treatments, follow your clinician's instructions. Follow-up and maintenance depend on response and tolerability.
Ask who manages your medications, how your usual clinician will receive updates, and whom to contact between visits. Neither a shortage designation nor local depression statistics show that ketamine is appropriate or effective for you. Consult a licensed physician.
Use these questions when you call or book a consultation with any Simpsonville provider.
Ask whether a physician, psychiatrist or anesthesiologist oversees each session and who you can reach afterward.
A good clinic reviews your history, medications, blood pressure and past treatments before recommending ketamine.
Look for continuous vital-sign monitoring and a calm, private recovery space.
IV infusions, Spravato® nasal spray, IM or sublingual options suit different goals and budgets.
Ask how the clinic coordinates with your therapist or offers integration support between sessions.
Request a written estimate for the first series and any maintenance sessions before you start.
| Clinic | Google rating | Reviews | Phone |
|---|---|---|---|
| MindWell Mental HealthGreenville | 4.8 | 200 | (864) 214-5335 |
| Infused Greenville, Greenville Ketamine CenterGreenville | 4.7 | 44 | (864) 438-1300 |
| Radial SpartanburgSpartanburg | 4.9 | 20 | (843) 703-1027 |
| Greenbrook Mental Wellness CentersGreenville | 4.6 | 19 | (855) 940-4867 |
| Life Line Services - Healing Substance AbuseGreenville | 4.3 | 10 | (864) 775-5509 |
Ratings come from public Google reviews and change over time. Listing order is not a medical recommendation.
Many patients travel a short distance for a clinic that fits their needs. Explore ketamine care in these nearby communities.
Browsing a wider area? See every clinic in Greenville County
Conditions Ketamine treats, county-wide options and guides written for South Carolina patients.